郑明奇

郑明奇，男，现任中国农业大学理学院博士生导师、教授。1990年至1997年，北京农业大学农药专业，攻读本科、硕士；1999年至2003年，中国农业大学农药专业，攻读博士学位；2006年至2007年，西澳大利亚大学（University of Western Australia, UWA）除草剂抗性研究中心（Australia Herbicide Resistance Initiative, AHRI），博士后研究。

主要从事“除草剂应用、杂草抗性分子机理和除草剂新作用靶标”相关的研究。迄今，已主持国家自然科学基金面上项目、公益性行业（农业）科研专项（子课题）、国际科技合作与交流专项、教育部留学回国人员启动基金等多项国家和省部级科研项目。此外，长期与农药企业合作开展新农药创制、农药使用、农药安全性评价等方面研究。以第一作者或通讯作者在国际知名期刊发表论文（SCI收录）10多篇；指导硕士、博士毕业生近20名。

• 杂草抗性调查及抗性分子机理：①系统调查了河北、河南、山东、陕西、山西等地区小麦田播娘蒿（Descurainia sophia L.）对苯磺隆（tribenuron-methyl）的抗性水平；深入研究播娘蒿对苯磺隆抗性的靶标抗性（target-site based resistance, TSR）和非靶标抗性（non-target-site based resistance, NTSR）的分子机理进行系统、深入研究。②系统调查了环洞庭湖和鄱阳湖地区小飞蓬（ Conyza canadensis L.）和牛筋草（Eleusine indica (L.) Gaertn）对草甘膦（glyphosate）抗性，并深入研究了小飞蓬对草甘膦抗性分子机理。

• 除草剂作用靶标研究：利用转录组测序（RNA-seq）技术，对具有高除草活性和选择性的甲氧基丙烯酸酯类化合物（CHM1080）作用靶标开展研究。

• 杂草治理系统解决方案：在抗性调查和抗性机理研究基础上，针对抗性杂草开展新型除草剂组合物的筛选和研究；针对不同作物全生长周期中杂草防控开展系统解决方案研究。

本科生课程：近十年课程数据
研究生课程：近十年课程数据

横向项目

论文题目	刊物名称	收录类别	发表年月	第一作者或全部作者	第一作者单位	排名
The Metabolism of a Novel Cytochrome P450 (CYP77B34) in Tribenuron-Methyl-Resistant Descurainia sophia L. to Herbicides with Different Mode of Actions	Int. J. Mol. Sci	SCI	2022, 5	Jing Shen	China Agricultural University	Corresponding author
Effects of a novel combination of two mutated acetolactate synthase (ALS) isozymes on resistance to ALS-inhibiting herbicides in flixweed (Descurainia sophia)	Weed Science	SCI	2021.03	Yufang Xu	China Agricultural University	corresponding author
Investigation of resistant level to tribenuron-methyl, diversity and regional difference of the resistant mutations on acetolactate synthase (ALS) isozymes in Descurainia sophia L. from China	Pesticide Biochemistry and Physiology	SCI	2020.07	Yufang Xu	China Agricultural University	corresponding author
Effects of resistance mutations of Pro197, Asp376 and Trp574 on the, characteristics of acetohydroxyacid synthase (AHAS) isozymes	Pest Management Science	SCI	2018, 74(8): 1870~1879	Yang Qian	China Agricultural University	Corresponding Author
Metabolic Resistance to Acetolactate Synthase Inhibiting Herbicide Tribenuron-Methyl in Descurainia sophia L. Mediated by Cytochrome P450 Enzymes	J. Agric. Food Chem	SCI	2018, 66, 4319−4327	Qian Yan	China Agricultural University	corresponding author
Investigation of resistance levels and mechanisms to nicosulfuron conferred by non-target-site mechanisms in Large Crabgrass (Digitaria sanguinalis L.) from China	Pesticide Biochemistry and Physiology	SCI	2017,141:84-89	Yu Mei	China Agricultural University	Corresponding Author
Resistance mutations of Pro197, Asp376 and Trp574 in the acetohydroxyacid synthase (AHAS) affect pigments, growths, and competitiveness of Descurainia sophia L	Scientific Reports	SCI	2017, 7(1): 16380	Yongzhi Zhang	China Agricultural University	Corresponding Author
Cross-resistance patterns to acetolactate synthase (ALS)-inhibiting herbicides of flixweed (Descurainia sophia L.) conferred by different combinations of ALS isozymes with a Pro-197-Thr mutation or a novelTrp-574-Leu mutation	Pesticide Biochemistry and Physiology	SCI	2017, 136: 41~45	Wei Deng	China Agricultural University	Corresponding Author
Target-site and non-target-site based resistance to the herbicide tribenuron-methyl in flixweed (Descurainia sophia L.)	BMC Genomics	SCI	2016, 17(1):551.	Qian Yang	China Agricultural University	Corresponding Author
Tribenuron- methyl resistance and mutation diversity of Pro197 in flixweed (Descurainia Sophia L.) accessions from China	Pesticide Biochemistry and Physiolog	SCI	2015,117:68-74	Wei Deng	China Agricultural University	Corresponding Author
Different cross-resistance patterns to AHAS herbicides of two tribenuron-methyl resistant flixweed (Descurainia sophia L.) biotypes in China,	Pesticide Biochemistry and Physiolog	SCI	2014,112:26-32	Wei Deng	China Agricultural University	Corresponding Author
Molecular basis of resistance to tribenuron-methyl in Descurainia Sophia (L.) populations from China	Pesticide Biochemistry and Physiolog	SCI	2012, 104:77-81	Xue jing Han	China Agricultural University	Corresponding Author
Cross-resistance pattern to four AHAS-inhibiting herbicides of tribenuron-methyl -resistant flixweed (Descurainia sophia) conferred by Asp-376-Glu mutation in AHAS	Journal of Integrative Agriculture	SCI	2016, 15(11): 2563–2570	Wei Deng	China Agricultural University	Corresponding Author

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