倪斌

倪斌博士，资源与环境学院教授，博士生导师。2021年2月以“杰出人才”引进中国农业大学植物营养系。2008-2014年毕业于中国科学院微生物研究所，师从我国著名环境与肠道微生物学家刘双江教授，获微生物学博士学位；2014-2020年在德国马普陆地微生物研究所从事博士后研究，师从著名微生物定量生物学家VictorSourjik教授。主要研究成果以第一或共同第一作者发表于PNAS, Cell Reports, FEMS Microbiology Reviews, ACS Synthetic Biology, Molecular Microbiology等国际学术期刊。

教育与工作经历：

2004.9-2008.6，理学学士学位，南京农业大学，国家生命科学与技术人才培养基地班
2008.9-2014.7，理学博士学位，中国科学院微生物研究所，微生物资源前期开发国家重点实验室
2014.7-2020.11，马普陆地微生物研究所，微生物系统与合成生物学系  
2021.2-至今，中国农业大学，资源与环境学院，养分资源高效利用全国重点实验室

发表论文：

1. Irina Lisevich, Remy Colin, Hao Yuan Yang, Bin Ni, Victor Sourjik. Physics and physiology determine strategies of bacterial investment in flagellar motility. bioRxiv, 2024.03. 30.587422

2. Manika Kargeti, Irina Kalita, Sarah Hoch, Maryia Ratnikava, Wenhao Xu, Bin Ni, Ron Leonard Dy, Remy Colin, Victor Sourjik. Experimental evolution of a reduced bacterial chemotaxis network. bioRxiv, 2024.03. 14.584839

3. Lu Guo†, Yun-Hao Wang†, Rui Cui†, Zhou Huang, Yuan Hong, Jia-Wei Qian, Bin Ni, An-Ming Xu, Cheng-Ying Jiang, Igor B. Zhulin*, Shuang-Jiang Liu*, De-Feng Li*. Attractant and repellent induce opposing changes in the four-helix bundle ligand-binding domain of a bacterial chemoreceptor. PLoS Biology. 2023, 21(12): e3002429.

4. Remy Colin†, Bin Ni†, Leanid Laganenka, Victor Sourjik*. Multiple functions of flagellar motility and chemotaxis in bacterial physiology. FEMS Microbiology Reviews, fuab038, https://doi.org/10.1093/femsre/fuab038.(共同一作)

5. Bin Ni†, Remy Colin†, and Victor Sourjik*. Production and characterization of motile and chemotactic bacterial minicells. ACS Synthetic Biology. 2021, 10(6): 1284–1291. (共同一作)

6. Bin Ni, Remy Colin, Hannes Link, Robert G Endres, Victor Sourjik*. Growth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxis. Proceedings of the National Academy of Sciences. 2020, 117(1):595-601.

7. Iaroslav Rudenko, Bin Ni, Timo Glatter, Victor Sourjik*. Inefficient secretion of anti-sigma factor FlgM inhibits bacterial motility at high temperature.iScience, 2019, 16(28): 145-154.

8. Yuan Hong, Zhou Huang, Lu Guo, Bin Ni, Cheng‐Ying Jiang, Xiao‐Jing Li, Yan‐Jie Hou, Wen‐Si Yang, Da‐Cheng Wang, Igor B Zhulin, Shuang‐Jiang Liu, De‐Feng Li. The ligand‐binding domain of a chemoreceptor from Comamonas testosteroni has a previously unknown homotrimeric structure. Molecular Microbiology, 2019, 112(3): 906-917.

9. Bin Ni, Bhaswar Ghosh, Ferencz S. Paldy, Remy Colin, Thomas Heimerl, Victor Sourjik*. Evolutionary remodeling of bacterial motility checkpoint control. Cell Reports. 2017, 24;18(4):866-877.

10. Zhou Huang, Bin Ni, Cheng-Ying Jiang, Yu-Fan Wu, Yun-Zhe He, Rebecca E. Parales, Shuang-Jiang Liu. Direct sensing and signal transduction during bacterial chemotaxis toward aromatic compounds in Comamonas testosteroni. Molecular Microbiology, 2016, 101(2):224-37.

11. Bin Ni, Zhou Huang, Yu-Fan Wu, Zheng Fan, Cheng-Ying Jiang, Shuang-Jiang Liu. A novel chemoreceptor MCP2983 from Comamonas testosteroni specifically binds to cis-aconitate and triggers chemotaxis towards diverse organic compounds. Applied Microbiology and Biotechnology. 2015, 99(6):2773-81.

12. Bin Ni, Zhou Huang, Zheng Fan, Cheng-Ying Jiang, Shuang-Jiang Liu. Comamonas testosteroni uses a chemoreceptor for tricarboxylic acid cycle intermediates to trigger chemotactic responses towards aromatic compounds. Molecular Microbiology, 2013, 90(4): 813-823.

13. Bin Ni, Yun Zhang, Dong-Wei Chen, Bao-Jun Wang, Shuang-Jiang Liu. Assimilation of aromatic compounds by Comamonas testosteroni: characterization and spreadability of protocatechuate 4,5-cleavage pathway in bacteria. Applied Microbiology and Biotechnology, 2013, 97(13): 6031-6041.

14. Rong Li, Jin-wei Zheng, Bin Ni, Kai Chen, Jian-chun Zhu, Shun-peng Li, Jian-dong Jiang. Biodegradation of pentachloronitrobenzene by newly isolated bacterium Labrys portucalensis pcnb-21. Pedosphere, 2011, 21(1): 31-36.

15. 蒋建东, 李荣, 陈凯, 倪斌, 李顺鹏. 多功能农药降解基因工程菌剂保藏条件研究. 农业环境科学学报, 2008, 27(4): 1686-1691.

学术兼职：

Microbiome, eLife, Soil Ecology Letters, Soil Science and Environment, Frontiers of Agricultural Science and Engineering, Soil Biology and Biochemistry, Environmental Microbiology, Applied Soil Ecology, Plant and Soil,  FEMS Microbiology  Ecology等杂志的审稿人.

中国植物营养学会根际营养专业委员会委员

中国植物营养学会生物与有机肥专业委员会委员

中国农业大学侨联第十届委员会委员

Stress Biology 编委

当代化工研究 编委

iMeta 青年编委

土壤学报 青年编委

课题组主要在实验室和田块尺度以玉米、小麦等粮食作物根际微生物群落为靶标，通过根际微生物组工程、微生物生理生化、微生物分子与遗传、微生物基因组设计、系统代谢工程、转录组、代谢组、微生物群落分析、计算机模拟等手段研究高产高效粮食生产体系的系统生物学设计法则，开发新型农业绿色投入品，实现微生物肥料与现代化肥工业的融合。

 具体研究内容如下：

 1. 根际微生物组工程与养分高效

 2. 根际微生物网络设计与调控

 3. 根际微生物系统与定量生物学

 4. 新型微生物源绿色投入品研发

研究生课程：近十年课程数据

纵向项目 其他项目

软件著作 专利

已毕业学生与第一就业单位

肖婷（硕士）: 北京市农业技术推广站

霍雯颖（中荷1+3项目）: 荷兰瓦赫宁根大学