孙兴明

孙兴明  博士，副教授。2010年获得河北师范大学理学学士学位，2017年获得中国农业大学农学博士学位，2018-2023年在中国农业大学从事博士后研究工作。2023年以高层次人才“青年研究员”身份引进至中国农业大学，主要从事稻种资源抗旱遗传解析及重要抗旱基因的功能研究。近年来已累计发表SCI论文16篇，分别发表在Nature Communications、New Phytologist、Journal of Experimental Botany 等国际主流期刊。主持国家自然科学基金青年项目、中国博士后科学基金面上项目等。获得中国农业大学优秀博士后荣誉称号。

1. 旱稻抗旱的遗传基础与基因调控机制

        抗旱一直以来是作物遗传学研究的热点、更是难点。我们课题组长期围绕栽培稻中的两种典型生态类型-水稻和旱稻，开展大规模的抗旱表型鉴定，通过正向遗传学方法解析旱稻抗旱的遗传基础。从旱稻中克隆了具有重大育种价值的抗旱基因DROT1，并发现其通过调控细胞壁结构特性来介导抗旱的分子机制。克隆了调控旱稻发达根系形成的基因RRS1，解析了其调控根系发育的分子机制。目前，我们已完成2000余份水、旱稻种质资源的田间抗旱表型鉴定和遗传解析，挖掘到多个重要抗旱基因，正在对其抗旱功能及其分子调控机理进行深入研究。

2. 水稻耐盐的遗传基础与基因调控机制

        我国有近5亿亩的盐碱地可以被开发利用，这是18亿亩耕地红线以外的重要储备耕地资源。对盐碱地的开发利用，已由过去的“改土适种”变为“以种适地”。因此，开展水稻的耐盐遗传学研究，发掘具有育种价值的耐盐基因，用于培育耐盐水稻新品种以适应盐碱地生长，对于充分利用边际土地来保障我国主粮的绝对安全具有重大意义。我们已利用2000余份水稻种质资源材料，开展了大田环境下的耐盐表型鉴定，并对水稻耐盐的遗传结构进行解析。目前，正在对多个重要耐盐基因开展功能验证、分子机理和育种应用研究。

未来工作重点

        我们将持续聚集水稻种质资源，重点从以下三个方面入手：（1）通过大田环境下的抗旱、耐盐表型鉴定，利用正向遗传学方法解析稻作抗旱、耐盐的遗传基础；（2）克隆抗旱、耐盐新基因，解析其发挥功能的分子调控机理；（3）发掘种质资源中的抗旱、耐盐基因优异自然变异，开发分子标记，用于水稻抗旱、耐盐的分子标记辅助育种。

已发表论文（#，第一作者；*，通讯作者）

1. Xingming Sun^#, Haiyan Xiong^#, Conghui Jiang, Dongmei Zhang, Zengling Yang, Yuanping Huang, Wanbin Zhu, Shuaishuai Ma, Junzhi Duan, Xin Wang, Wei Liu, Haifeng Guo, Gangling Li, Jiawei Qi, Chaobo Liang, Zhanying Zhang, Jinjie Li, Hongliang Zhang, Lujia Han, Yihua Zhou, Youliang Peng & Zichao Li*. Natural variation of DROT1 confers drought adaptation in upland rice. Nature Communications. 2022, 13: 4265. (同期被Nature Plants期刊评选为Research Highlight进行报道。详见：Lyu, J. Strengthen the wall. Nat. Plants 8, 869 (2022). https://doi.org/10.1038/s41477-022-01234-7)

2. Jie Gao^#, Yong Zhao^#, Zhikun Zhao, Wei Liu, Conghui Jiang, Jinjie Li, Zhanying Zhang, Hongliang Zhang, Yage Zhang, Xiaoning Wang, Xingming Sun* & Zichao Li*. RRS1 shapes robust root system to enhance drought resistance in rice. New Phytologist. 2023, https://doi.org/10.1111/nph.18775.（同期被Wiley’s出版社评选为Research Headlines，由编辑撰写题为“Blocking gene that inhibits root growth mayenhance drought resistance in crops”的评论，在其官方科学媒体进行报道。详见：http://phys.org/news/2023-03-blocking-gene-inhibits-root-growth.html）。

3. Xingming Sun^#, Zhanying Zhang^#, Chao Chen^#, Wei Wu, Nannan Ren, Conghui Jiang, Jianping Yu, Yan Zhao, Xiaoming Zheng, Qingwen Yang, Hongliang Zhang, Jinjie Li & Zichao Li*. The C-S-A gene system regulates hull pigmentation and reveals evolution of anthocyanin biosynthesis pathway in rice. Journal of Experimental Botany. 2018, 69(7): 1485-1498. (截止2023年6月，已被引用91次)

4. Xingming Sun^#, Zhanying Zhang, Jinjie Li, Hongliang Zhang, Youliang Peng & Zichao Li*. Uncovering hierarchical regulation among MYB-bHLH-WD40 proteins and manipulating anthocyanin pigmentation in rice. International Journal of Molecular Science. 2022, 23(15), 8203.

5. Zhanying Zhang^#, Xingming Sun^#, Xiaoqian Ma, Bingxia Xu, Yong Zhao, Zhiqi Ma, Gangling Li, Najeeb Ullah Khan, Yinghua Pan, Yuntao Liang, Hongliang Zhang, Jinjie Li & Zichao Li*. GNP6, a novel allele of MOC1, regulates panicle and tiller development in rice. The Crop Journal. 2021, 9(1): 57-67.

参与发表的部分论文

1.  Gangling Li^#, Bingxia Xu^#, Yanpei Zhang, Yawen Xu, Najeeb Ullah Khan, Jianyin Xie, Xingming Sun, Haifeng Guo, Zhenyuan Wu, Xueqiang Wang, Hongliang Zhang, Jinjie Li, Jianlong Xu, Wensheng Wang, Zhanying Zhang*, Zichao Li*. RGN1 controls grain number and shapes panicle architecture in rice. Plant Biotechnology Journal. 2022, 20(1):158-167.

2.  Yingxiu Li^#, Shichen Han^#, Xingming Sun, Najeeb Ullah Khan, Qun Zhong, Zhanying Zhang, Hongliang Zhang, Feng Ming, Zichao Li, Jinjie Li*. Variations in OsSPL10 confer drought tolerance by directly regulating OsNAC2 expression and ROS production in rice. Journal of Integrative Plant Biology. 2022, https://doi.org/10.1111 /jipb.13414.

3.  Yanpei Zhang^#, Zhanying Zhang^#, Xingming Sun, Xiaoyang Zhu, Ben Li, Jinjie Li, Haifeng Guo, Chao Chen, Yinghua Pan, Yuntao Liang; Zhijian Xu, Hongliang Zhang, Zichao Li*. Natural alleles of GLA for grain length and awn development were differently domesticated in rice subspecies japonica and indica. Plant Biotechnology Journal. 2019, 17(8):1547-1559.

4.  Jianping Yu^#, Jinli Miao^#, Zhanying Zhang, Haiyan Xiong, Xiaoyang Zhu, Xingming Sun, Yinghua Pan, Yuntao Liang, Qiang Zhang, M.A.R. Rashid, Jinjie Li1, Hongliang Zhang*, Zichao Li*. Alternative splicing of OsLG3b controls grain length and yield in japonica rice. Plant Biotechnology Journal. 2018, 16(9): 1667–1678.

5.  Zhanying Zhang^#, Jinjie Li^#, Zuoshun Tang^#, Hongliang Zhang, Xingming Sun, Jianping Yu, Guoxin Yao, Gangling Li, Haifeng Guo, Jilong Li, Huamao Wu, Hanguang Huang, Yawen Xu, Zhigang Yin, Yanhua Qi, Rongfeng Huang, Weicai Yang and Zichao Li*. Gnp4/LAX2, a RAWUL protein, modulates grain length by interfering with OsIAA3-OsARF25 interaction in rice. Journal of Experimental Botany. 2018, 20(69): 4723-4737.

6.  Zhanying Zhang^#, Jinjie Li^#, Yinghua Pan^#, Jilong Li^#, Lei Zhou^#, Hongli Shi^#, Yawen Zeng, Haifeng Guo, Shuming Yang, Weiwei Zheng, Jianping Yu, Xingming Sun, Gangling Li, Yanglin Ding, Liang Ma, Shiquan Shen, Luyuan Dai, Hongliang Zhang, Shuhua Yang, Yan Guo, Zichao Li*. Natural variation in CTB4a enhances rice adaptation to cold habitats. Nature Communications. 2017, 8:14788.

本科生课程：近十年课程数据
研究生课程：近十年课程数据

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