姜力

中国农业大学动物科技学院副教授，博士生导师，先后主持和参加国家自然科学基金、北京市自然科学基金、国家重点研发计划、科技创新2030重大课题等多个项目。主要研究方向为分子数量遗传学、家畜重要性状功能基因挖掘和分子遗传机制解析、分子抗病育种和功能基因组研究、分子标记辅助选择和基因组选择等。目前主要围绕猪和奶牛公畜精液品质性状遗传基础解析、猪遗传缺陷病功能基因挖掘和分子机制解析、胚胎干细胞育种方面进行相关研究。以第一作者或通讯作者发表SCI论文近30篇，授权发明专利7项，软件著作权1项，参编教材及著作3部，研究成果分别获得 “国家科技进步奖”二等奖”、“北京市科学技术奖”一等奖和“北京市科学技术奖”二等奖。

中国奶业协会育种专业委员会成员

主要研究方向为分子数量遗传学、家畜重要性状功能基因挖掘和分子遗传机制解析、分子抗病育种和功能基因组研究、分子标记辅助选择和基因组选择等。目前聚焦猪和奶牛公畜精液品质性状遗传基础解析、猪遗传缺陷病功能基因挖掘和分子机制解析、胚胎干细胞育种方面进行相关研究。

本科生课程：近十年课程数据
研究生课程：近十年课程数据

纵向项目 横向项目

论文题目	刊物名称	收录类别	发表年月	第一作者或全部作者	第一作者单位	排名

(1) Cao J^#, Leng B^#, Zhang Chun, Wang Y, Zhang Y, Zheng X, Zhang Y, Li Y, Jiang L*: Proteomic signatures of sperm and extracellular vesicles associated with sperm freezability in Holstein bulls. Scientific Reports, 2026, 16:6934.

(2) Chen Z, Zhang X, Teng J, Jiang L*, Zhang Q*: HSF1 and CPSF1 affect milk fat and protein synthesis by regulating the AKT/mTOR signaling pathway. Journal of Animal Science, 2025, 103, skaf009.

(3) Ding N, Zhang Y, Wang J, Liu J, Zhang J, Zhang C, Zhou L, Cao J, Jiang L*: Lipidomic and transcriptomic characteristics of boar seminal plasma extracellular vesicles associated with sperm motility. BBA - Molecular and Cell Biology of Lipids, 1870(2025), 159561.

(4) Zhang X, Teng J, Chen Z, Zhao C, Jiang L*, Zhang Q*: S100A9 affects milk protein content by regulating amino acid transporters and the PI3K-Akt, WNT, and mTOR signaling pathways. Genes, 2024,15, 1486

(5) Zhang Y, Ding N, Cao J, Zhang J, Liu J, Zhang C, Jiang L*: Proteomics and Metabolic Characteristics of Boar Seminal Plasma Extracellular Vesicles Reveal Biomarker Candidates Related to Sperm Motility. Journal of proteome, 2024, 23, 3764-3779.

(6) Ding N, Zhang Y, Huang M, Liu J, Wang C, Zhang C, Cao J, Zhang Q, Jiang L*: Circ-CREBBP inhibits sperm apoptosis via the PI3KAkt signaling pathway by sponging miR-10384 and miR-143-3p. Communications Biology, 2022, 5: 1339.

(7) Ding Y, Ding N, Zhang Y, Xie S, Huang M, Ding X, Dong W, Jiang L^*: MicroRNA-222 transferred from semen extracellular vesicles inhibits sperm apoptosis by targeting BCL2L11. Frontiers in Cell and Developmental Biology, 2021, 9: 736864.(8) Zhang Y, Ding N, Xie S, Ding Y, Mengna Huang, Ding X, Jiang L^*: Identification of important extracellular vesicle RNA molecules related to sperm motility and prostate cancer. Extracellular Vesicles and Circulating Nucleic Acids, 2021, 2: 104-26.

(9) Dong W, Ding N, Zhang Y, Tan Z^*, Ding X, Zhang Q, Jiang L^*: Alterations of suckling piglet jejunal microbiota due to infection with porcine epidemic diarrhea virus and protection against infection by Lactobacillus salivarius. Frontiers in veterinary science, 2021, 8: 771411.

(10) Dong W, Yang J, Zhang Y, Liu S, Ning C, Ding X, Wang W, Zhang Y, Zhang Q, Jiang L^*:  Integrative analysis of genome-wide DNA methylation and gene expression profiles reveals important epigenetic genes related to milk production traits in dairy cattle. Journal of Animal Breeding and Genetics, 2021, 138:562-573.

(11) Tan Z, Dong W, Ding Y, Ding X, Zhang Q, Jiang L^*: Porcine Epidemic Diarrhea Altered Colonic Microbiota Communities in Suckling Piglets. Genes (Basel), 2020, 11, 44.

(12) Yin H, Zhou C, Shi S, Fang L, Liu J, Sun D, Jiang L^*, Zhang S^*: Weighted Single-Step Genome-Wide Association Study of Semen Traits in Holstein Bulls of China. Frontiers in Genetics, 2019, 10:1053.

(13) Tan Z, Dong W, Ding Y, Ding X, Zhang Q, Jiang L^*: Changes in cecal microbiota community of suckling piglets infected with porcine epidemic diarrhea virus. PLoS One, 2019, 14: e0219868.

(14) Wang D, Ning C, Liu JF, Zhang Q, Jiang L^*: Short communication: Replication of genome-wide association studies for milk production traits in Chinese Holstein by an efficient rotated linear mixed model. Journal of Dairy Science, 2019, 102(3): 2378-2383.

(15) Zheng X^#, Jiang L^#, Ning C, Hu Z, Zhou L, Yu Y, Zhang S, Liu J ^*: A novel mutation in the promoter region of RPL8 regulates milk fat traits in dairy cattle by binding transcription factor Pax6. Biochim Biophys Acta Mol Cell Biol Lipids, 2019, 1864, 158528.

(16) Yang J, Liu X, Wang D, Ning C, Wang H, Zhang Q, Jiang L^*: Functional validation of GPIHBP1 and identification of a functional mutation in GPIHBP1 for milk fat traits in dairy cattle. Scientific Reports, 2017, 7(1):8546.

(17) Liu X, Yang J, Zhang Q, Jiang L^*: Regulation of DNA methylation on EEF1D and RPL8 expression in cattle. Genetica, 2017, 145, 387-95.

(18) Yang J, Jiang J, Liu X, Wang H, Guo G, Zhang Q, Jiang L^*: Differential expression of genes in milk of dairy cattle during lactation. Anim Genet, 2016, 47, 174-80.

(19) Jiang L^#, Liu X^#, Yang J, Wang H, Jiang J, Liu L, He S, Ding X, Liu J, Zhang Q^*: Targeted resequencing of GWAS loci reveals novel genetic variants for milk production traits. BMC Genomics, 2014, 15, 1105.

(20) Yang J, Liu X, Zhang Q, Jiang L^*: Identification and quantitative mRNA analysis of a novel splice variant of GPIHBP1 in dairy cattle. J Anim Sci Biotechnol, 2014, 5, 50.

(21) Wang H^#, Jiang L^#, Wang W, Zhang S, Yin Z, Zhang Q, Liu J^*: Associations between variants of the HAL gene and milk production traits in Chinese Holstein cows. BMC Genet, 2014, 15, 125.

(22) Jiang L, Jiang J, Yang J, Liu X, Wang J, Wang H, Ding X, Liu J, Zhang Q^*: Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins. BMC Genomics, 2013, 14, 131.

(23) Wang H^#, Jiang L^#, Liu X, Yang J, Wei J, Xu J, Zhang Q,Liu J: A post-GWAS replication study confirming the PTK2 gene associated with milk production traits in Chinese Holstein. PLoS One, 2013, 8, e83625.

(24) Jiang L, Jiang J, Wang J, Ding X, Liu J, Zhang Q^*: Genome-wide identification of copy number variations in Chinese Holstein. PLoS One, 2012, 7, e48732.

(25) Jiang L, Liu J, Sun D, Ma P, Ding X, Yu Y, Zhang Q^*: Genome wide association studies for milk production traits in Chinese Holstein population. PLoS One, 2010, 5, e13661.

(26) Jiang L, Zhao F, Zhang Q^*: Simulation of gene pyramiding in Drosophila melanogaster. Journal of Genetics and Genomics, 2008, 35, 737-42.

(27) 张鼎新，冷秉雯，罗蓊昀，王祉媛，张勤，姜力^*. 猪一般恢复力性状遗传参数估计. 畜牧兽医学报，2025.

(28) 李晓彤，王鹏宇，放颖妍，于鸿希，张毅，王雅春，张元沛，李彦芹，姜力^*. 公牛精子耐冻性相关基因多态位点的挖掘与功能验证. 畜牧兽医学报，2025.

(29) 石庆珍，徐鸿洋，张燕，张毅，王雅春，韩建永，姜力^*. 基于不同方法的微量细胞全基因组遗传变异检测和比较分析. 畜牧兽医学报，2024.

(30) 丁亚群，丁宁，谢深民，黄梦娜，张昱，张勤，姜力^*. VPS28 基因敲除小鼠模型的构建及其对泌乳和免疫性状影响的研究. 生物技术通报, 2022.

软件著作 专利