李孟华

湖北黄冈人。中国农业大学，教授（二级），博士生导师。国家杰出青年基金获得者（2018年），国家重点研发计划首席科学家（2021年）；中国农业大学领军教授（A类，2020年）、国家级创新团队负责人（2020年）；中国科学院“百人计划”引进海外杰出人才（A类， 2011年），山东省“泰山学者”特聘专家（2015年）。1993-1997年，华中农业大学，畜牧专业本科；1998-2003年，博士毕业于华中农业大学畜牧兽医学院动物遗传育种与繁殖专业；2003年-2010年先后在芬兰农业食品科学研究院、赫尔辛基大学从事博士后研究，其间受欧盟邀请任挪威生命科学技术大学和意大利米兰圣心天主教大学短期访问学者; 2010年至2011年任芬兰农业食品科学研究院研究员(PI); 2011年-2019年任中国科学院动物研究所研究员。2019年12月至今任中国农业大学教授（二级），其中曾任动物科学技术学院院长助理、副院长，中国农业大学图书馆馆长。

国际动物遗传学会羊专业委员会主席（2019年8月-），国际动物学会反刍动物学专业委员会主任委员（2025年1月-），中国畜牧兽医学会动物遗传育种学分会副理事长（2025年7月-），中国遗传学会动物遗传学专业委员会副主任委员（2025年1月-），中国动物学会理事会理事（2024年8月-）

羊遗传与种质创新； 基因组学；群体遗传学；计算组学；大数据分析；生物信息学

本科生课程：近十年课程数据

纵向项目 横向项目

Luo LY#., Wu H#., ….., Jia SG*, Wang WM*, Li M-H* T2T of sheep reveals variants associated with wool fines. Nature Genetics 2025, 57, 218–230 (本人标注: 最后共同通讯作者)

 

Xu Songsong,Zhanerke Akhatayeva,Jiaxin Liu,Xueyan Feng,Yi Yu,Bouabid Badaoui,Ali Esmailizadeh,Juha Kantanen,Marcel Amills,Johannes A. Lenstra,Anna M. Johansson,David W. Coltman,George E. Liu,Ino Curik,Pablo Orozco-terWengel,Samuel R. Paiva,Natalia A. Zinovieva,Linwei Zhang,Ji Yang,Zhihong Liu,Yachun Wang,Ying Yu, Meng-Hua Li. SCIENCE CHINA-Life Sciences, 2025, 68:934-960. (本人标注: 唯一通讯作者)

 

Wu H#, Luo LY#., ……..Jia SG*, Liu ZH*, Li M-H* T2T genome assembly of a male goat reveals variants for cashmere traits. Nature Communications 2024, 15:10041. (本人标注: 最后共同通讯作者)

 

Yang J., Wang D.F., Huang J. H., …, Li M.-H.* Structural variant landscapes reveal convergent signatures of evolution in sheep and goats. Genome Biology 2024, 25:148.(期刊论文) (本人标注: 唯一通讯作者)

 

Yan Z.#, Yang J.#, …, Li M.-H*. A time-resolved multi-omics atlas of transcriptional regulation in response to high-altitude hypoxia across whole-body tissues. Nature Communications 2024, 15:3970 (期刊论文) (本人标注: 唯一通讯作者)

 

Lv  Feng-Hua, Wang Dong-Feng Wang , Zhao Si-Yi , Lv Xiao-Yang, Sun  Wei, Nielsen Rasmus, Meng-Hua Li. Deep ancestral introgressions between ovine species shape sheep genomes via argali-mediated gene flow. Molecular Biology and Evolution 2024, 41: msae212.

 

Deng J.#, Liu YJ,… , Li L.*, Li M.-H.*. Single-cell transcriptome and metagenome profiling reveals the genetic basis of rumen functions and convergent developmental patterns in ruminants. Genome Research, 2023,33:1690-1707(期刊论文) (本人标注: 最后共同通讯作者)

 

Li X.#, He S.-G.#, Li W.-R.#,…, Liu M.-J.*; Li M.-H.*. Genomic analyses of wild argali, domestic sheep, and their hybrids provide insights into chromosome evolution, phenotypic variation, and germplasm innovation. Genome Research,2022,32(9):1669-1684 (期刊论文) (本人标注: 最后共同通讯作者)

 

Lv F.-H., Cao Y.-H., Liu G.-J., …, Li M.-H.*. Whole-genome resequencing of worldwide wild and domestic sheep elucidates genetic diversity, introgression, and agronomically important loci. Molecular Biology and Evolution,2022,39(2):msab353 (期刊论文) (本人标注: 唯一通讯作者)

 

Li X.#, Yang J.#, Shen M.#, Xie X.-L.#, Liu G.-J.#, …,X.-H. Wang*, Li M.-H.*.Whole-genome resequencing of wild and domestic sheep identifies genes associated with morphological and agronomic traits. Nature Communications,2020,11:2815 (期刊论文) ( 本人标注: 最后共同通讯作者 )

 

Deng J., Xie X.-L.,…, Li M.-H.* Paternal Origins and Migratory Episodes of Domestic Sheep. Current Biology, 2020,30(20):4085-4095 (期刊论文) (本人标注: 唯一通讯作者)

 

Wu M.,…,Li M.-H.*; Lv F.-H*. Artificial selection shapes the lower genomic diversity and higher selective pressures on the sex chromosomes of domestic animals. SCIENCE CHINA-Life Sciences,2024:1-4 (期刊论文) (本人标注: 共同通讯作者)

 

Xu Y.-X.#, Wang B.#,…, Li M.-H.*,Lv F.-H*. Whole-body adipose tissue multi-omic analyses in sheep reveal molecular mechanisms underlying local adaptation to extreme environments. Communications Biology,2023,6(1):159(期刊论文) (本人标注: 共同通讯作者)

 

Cao Y.-H.#,Xu S.-S.#,Shen M.#, Chen Z.-H.#, Gao L.#,…, Li M.-H.*. Historical introgression from wild relatives enhanced climatic adaptation and resistance to pneumonia in sheep. Molecular Biology and Evolution,2021,38(3):838-855 (期刊论文) ( 本人标注: 唯一通讯作者 )

 

Chen Z.-H.#, Xu Y.-X.#, …,Rasmus Nielsen; Li M.-H*. Whole-genome sequence analysis unveils different origins of European and Asiatic mouflon and domestication-related genes in sheep. Communications Biology, 2021,4:1307 (期刊论文) (本人标注: 唯一通讯作者)

 

Xiao-Ju Hu#, Ji Yang#, Xing-Long Xie#, Feng-Hua Lv#, Yin-Hong Cao ,Wen-Rong Li, Ming-Jun Liu, Yu-Tao Wang, Jin-Quan Li, Yong-Gang Liu，Yan-Lin Ren, Zhi-Qiang Shen, Feng Wang, EEr Hehua, Jian-Lin Han, Meng-Hua Li* (2019) The genome landscape of Tibetan sheep reveals adaptive introgression from argali and the history of early human settlements on the Qinghai-Tibetan Plateau. Molecular Biology and Evolution 36:283-303.

 

5.  Zhao Yong-Xin(#),Yang Ji(#), Lv Feng-Hua(#),Hu Xiao-Ju, Xie Xing-Long, Zhang Min, Li Wen-Rong, Liu Ming-Jun, Wang Yu-Tao, Li Jin-Quan, Liu Yong-Gang, Ren Yan-Ling, Wang Feng, Eer Hehua, Kantanen,   JuhaLenstra, Johannes Arjen, Han Jian-Lin, Li Meng-Hua* (2017) Genomic reconstruction of the history of native sheep reveals the peopling patterns of nomads and the expansion of early pastoralism in East Asia. Molecular Biology and Evolution 34:2380-2395.

 

Ji Yang#, Wen-Rong Li#, Feng-Hua Lv#, San-Gang He#, Shi-Lin Tian#, Wei-Feng Peng, Ya-Wei Sun, Yong-Xin Zhao, Xiao-Long Tu, Min Zhang, Xing-Long Xie, Yu-Tao Wang, Jin-Quan Li, Yong-Gang Liu, Zhi-Qiang Shen, Feng Wang, Guang-Jian  Liu, Hong-Feng  Lu, Juha Kantanen, Jian-Lin Han, Meng-Hua Li* and Ming-Jun Liu*（2016） Whole-Genome    Sequencingof Native  Sheep Provides Insights into    Rapid Adaptations to Extreme Environments. Molecular Biology and Evolution 33(10): 2576–2592.

 

Lv F-H, Peng W-F, Yang J, Zhao Y-X, Li W-R, Liu M-J, Ma Y-H, Zhao Q-J, Yang G-L, Wang F, Li J-Q, Liu Y-G, Shen Z-Q, Zhao S-G, Hehua E, Gorkhali NA, Farhad Vahidi SM, Muladno M, Naqvi AN, Tabell J, Iso-Touru T, Bruford MW, Kantanen J, Han J-L*, Li M-H* (2015). Mitogenomic Meta-Analysis Identifies Two Phases of Migration in the History of EasternEurasian Sheep. Molecular Biology and Evolution 32: 2515-2533.

 

Feng-Hua Lv, Saif Agha, Juha Kantanen, LiciaColli, Sylvie Stucki, James W. Kijas, Stéphane Joost, Meng-Hua Li*, Paolo Ajmone Marsan (2014) Adaptations to Climate-Mediated Selective Pressures   in Sheep. Molecular Biology and Evolution 31: 3324-3343.

 

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