于可济

于可济，本科和博士毕业于中国农业大学，美国北德克萨斯大学BioDiscovery Institute联合培养博士，北京林业大学林木分子设计育种高精尖创新中心博士后，2024年加入中国农业大学任副教授。主要从事葡萄果实成涩物质代谢机理及葡萄酒涩感评价相关领域的研究。近年研究成果包括：阐明了葡萄(+)-儿茶素型缩合单宁聚合过程的延伸单元预组装机制、揭示了 LAR 蛋白调控葡萄缩合单宁聚合度的酶学基础、发现了精细调控葡萄缩合单宁和花色苷流向分配的关键转录因子、建立了衡量酿酒葡萄果实缩合单宁聚合进程的检测手段等，为定向调控葡萄与葡萄酒涩感品质提供了重要理论依据；相关成果以第一作者或通讯作者在Nat. Commun.、Plant Commun.、Plant Physiol.、Plant Physiol. Bioch.、Front. Plant Sci.等学术期刊发表，并授权发明专利1项。

中国食品工业协会国家葡萄酒（果酒）国家评委

期刊Food Innovation and Advances青年编委

期刊Modern Agriculture副编委

1. 植物次生代谢途径解析

2. 葡萄果实风味品质调控

3. 葡萄酒风味化学

结合质谱高通量检测与化合物结构解析、天然产物合成与纯化、微生物与植物遗传转化、蛋白表达与酶学性质表征、分子对接与虚拟筛选、转录组数据挖掘等技术，解析关键风味物质在葡萄果实发育和葡萄酒酿造过程中的形成机理，并应用于葡萄原料品质及葡萄酒风格的靶向调控。

代表性论文（^*通讯作者，^#并列一作）

Yu K, Dixon R A, Duan C*. A role for ascorbate conjugates of (+)-catechin in proanthocyanidin polymerization[J]. Nature Communications, 2022, 13(1): 3425. (5 Year IF: 17.0/ TOP10)

Yu K, Song Y, Lin J*, Dixon R A*. The complexities of proanthocyanidin biosynthesis and its regulation in plants[J]. Plant Communications, 2023, 4(2). (5 Year IF: 10.5/ TOP10)

Yu K, Jun J H, Duan C, Dixon R A*. VvLAR1 and VvLAR2 are bifunctional enzymes for proanthocyanidin biosynthesis in grapevine[J]. Plant Physiology, 2019, 180(3): 1362-1374. (5 Year IF: 8.8/ TOP10)

Song Y^#, Yu K^#, Zhang S, Li Y, ..., Zhang X, Li R, Dixon R A, Lin J*. Poplar glutathione S-transferase PtrGSTF8 contributes to reactive oxygen species scavenging and salt tolerance[J]. Plant Physiology and Biochemistry, 2024: 108766. (5 Year IF: 6.4/ TOP10)

Li M, Pei X, Shi N, Yang Y, ..., Duan C, Yu K*, Wang J*. Volatomic differences among Vitis amurensis cultivars and its hybrids with V. Vinifera revealed the effects of genotype, region, and vintage on grape aroma[J]. Food Research International, 2024: 114726. (5 Year IF: 7.7/ TOP10)

Guo Y, Wang S, Yu K, Wang H, …, Li Y, Song G, Dixon R A*, Lin J*. Manipulating microRNA miR408 enhances both biomass yield and saccharification efficiency in poplar[J]. Nature Communications, 2023, 14(1): 4285. (5 Year IF: 17.0/ TOP10)

Shi T, Su Y, Lan Y, Duan C, Yu K*. The molecular basis of flavonoid biosynthesis response to water, light, and temperature in grape berries[J]. Frontiers in Plant Science, 2024, 15: 1441893. (5 Year IF: 6.8/ TOP10)

Zhao K, Lan Y, Shi Y, Duan C, Yu K*. Metabolite and transcriptome analyses reveal the effects of salinity stress on the biosynthesis of proanthocyanidins and anthocyanins in grape suspension cells[J]. Frontiers in Plant Science, 2024, 15: 1351008.(5 Year IF: 6.8/ TOP10)

Cheng J, Shi Y, Wang J, Duan C, Yu K*. Transcription factor VvibHLH93 negatively regulates proanthocyanidin biosynthesis in grapevine[J]. Frontiers in Plant Science, 2022, 13:1007895. (5 Year IF: 6.8/ TOP10)

Cheng J, Yu K, Shi Y, Wang J, Duan C*. Transcription factor VviMYB86 oppositely regulates proanthocyanidin and anthocyanin biosynthesis in grape berries[J]. Frontiers in Plant Science, 2021, 11: 613677. (5 Year IF: 6.8/ TOP10)

发明专利

段长青, 于可济, 兰义宾, 齐梦瑶. 4-(O-抗坏血酸)-(+)-儿茶素的应用及2,3-反式无色花青素检测方法:中国, ZL 20211127183.4[P]. 2021-10-29.

本科生课程：近十年课程数据
研究生课程：近十年课程数据

软件著作 专利

农业农村部葡萄酒加工重点实验室官方微信公众号：

农业农村部葡萄酒加工重点实验室官方网址：http://vel.spxy.cau.edu.cn/