张博

张博，博士生导师。主要研究方向为畜禽遗传资源挖掘、保护和利用。入选中国农业大学优秀人才，曾任农业农村部种业管理司创新发展处借调人员。先后主持国家自然科学青年基金、科技创新2030-农业生物育种项目子课题、北京市自然科学基金面上项目、山东省自然科学青年基金、中国博士后科学基金等资助的科研项目10余项，参与国家重点研发计划、国家家养动物种质资源库建设等项目。获得国家级标准1项，省部级标准3项，国家发明专利4项，省部级科学技术一等奖1项（排名第3）。先后在Scientific Data、Food Research International、Journal of Animal Science and Biotechnology等杂志上发表论文30余篇。

1.畜禽遗传资源保护和利用，优良地方品猪特色性状基因的挖掘；

2.畜禽优良肉质基因的挖掘；

3.家禽性别遗传机制。

本科生课程：近十年课程数据
研究生课程：近十年课程数据

论文题目	刊物名称	收录类别	发表年月	第一作者或全部作者	第一作者单位	排名

1. Nie J, Cheng W, Tao Z, Dong X, Yan D*, Zhang B*, Zhang H*. Single-nucleus atlas of porcine longissimus dorsi development reveals breed-specific myofiber maturation and stromal remodeling. Food Res Int. 2026:242.

2. Sun X, Liu R, Sun Y, Luo P, Zhang B*, Zhang H*. Single-nucleus profiling of neonatal broilers identifies early molecular signatures associated with the divergence in the potential of meat quality. Food Res Int. 2026,240:119690.

3. Li P, Cheng W, Shang P, Tao Z, Zhang H, Zhang B*. circRNA-associated ceRNA regulatory networks in cardiac responses to high-altitude hypoxia in Tibetan pigs (sus scrofa). Int J Mol Sci. 2026,27(10):4392.

4. Zhao Z, Nie R, Fan H, Ngodroup T, Zhu L, Pan H, Zhang B*, Zhang H*. large-scale genomics reveals three-source ancestry and layered adaptation to high altitude in Tibetan chickens. Adv Sci (Weinh). 2026:e22994.

5. Nie J, Fu Y, Hao X, Yan D, Zhang B*, Zhang H*. Porcine FRZB (sFRP3) negatively regulates myogenesis via the Wnt signaling pathway. Animals (Basel). 2026,16(2):276.

6. Chen X, Peng D, Zang L, Xian L, Feng J, Zhang H, Zhang B*.Identification of candidate genes for hypoxic adaptation through transcriptomic data of embryo hearts in Xueyu White Chickens. Poult Sci. 2026,105(1):106078.

7. Chen X,FanH,ZhangH,PengD, ZhangB*.Transcriptome data revealshypoxic adaptability on embryonic cardiac development in tibetan chickens.Agriculture-basel,2026, 16(2): 244

8. Liu R, Miao H, Zhang B*, Zhang H. Identification of key differentially expressed genes during early sex determination in chicken embryos. Int J Mol Sci. 2025,26(19):9575.

9. Li P, Cheng W, Pubu Z, Shang P, Zhang H, Zhang B*. Comprehensive transcriptome analysis reveals MSTRG.19853.1/ssc-miR-361-3p/NPPA axis is related to hypoxic adaptation in Tibetan pigs. BMC Genomics. 2025,26(1):595.

10. Fu Y, Hao X, Shang P, Nie J, Chamba Y, Zhang B*, Zhang H*. MUSTN1 interaction with SMPX regulates muscle development and regeneration. Cell Prolif. 2025,58(6):e13809.

11. Liu R, Zhang P, Bai J, Zhong Z, Shan Y, Cheng Z, Zhang Q, Guo Q, Zhang H, Zhang B*. Integrated transcriptomic and proteomic analyses of antler growth and ossification mechanisms. Int J Mol Sci. 2024, 25(23):13215.

12. Zhang W, Chen X, Nie R, Guo A, Ling Y, Zhang B*, Zhang H*. Single-cell transcriptomic analysis reveals regulative mechanisms of follicular selection and atresia in chicken granulosa cells. Food Res Int. 2024,198:115368.

13. Yang R, Jin S, Fang S, Yan D, Zhang H, Nie J, Liu J, Lv M,Zhang B*, Dong X*. Genetic introgression from commercial European pigs to the indigenous Chinese Lijiang breed and associated changes in phenotypes. Genet Sel Evol. 2024,56(1):24.

14. Nie R, Zhang W, Tian H, Li J, Ling Y,Zhang B*, Zhang H*, Wu C. Regulation of follicular development in chickens: WIF1 modulates granulosa cell proliferation and progesterone synthesis via Wnt/β-Catenin signaling pathway. Int J Mol Sci. 2024,25(3):1788.

15. Zhang Y, Zhang B*, Zhang Y, Nie R, Zhang J, Shang P, Zhang H. Chromosome-level genome assembly of the bar-headed goose (Anser indicus). Sci Data. 2022,9(1):668.

16. Fu Y, Hao X, Shang P, Chamba Y, Zhang B*, Zhang H*. Functional identification of porcine DLK1 during muscle development. Animals (Basel). 2022,12(12):1523.

17. Tian W, Hao X, Nie R, Ling Y, Zhang B*, Zhang H*, Wu C.Comparative transcriptome analysis reveals regulatory mechanism of long non-coding RNAs during abdominal preadipocyte adipogenic differentiation in chickens. Animals (Basel). 2022,12(9):1099.

18. Zhang P, Fu Y, Zhang R, Shang P, Zhang H,Zhang B*. Association of KCTD15 gene with fat deposition in pigs. J Anim Physiol Anim Nutr (Berl). 2022,106(3):537-544.

19. Duan M, Wang Z, Guo X, Wang K, Liu S, Zhang B*, Shang P*. Integrated analysis of transcriptomic and proteomic analyses reveals different metabolic patterns in the livers of Tibetan and Yorkshire pigs. Anim Biosci. 2021,34(5):922-930.

20. Zhang B, Ban D, Gou X, Zhang Y, Yang L, Chamba Y, Zhang H. Genome-wide DNA methylation profiles in Tibetan and Yorkshire pigs under high-altitude hypoxia. J Anim Sci Biotechnol. 2019,10:25.

21. Zhang B, Shang P, Tao Z, Qiangba Y, Wang Z, Zhang H. Effect of a single nucleotide polymorphism in the growth hormone secretagogue receptor (GHSR) gene on growth rate in pigs. Gene. 2017,634:68-73.

22. Zhang B, Chamba Y, Shang P, Wang Z, Ma J, Wang L, Zhang H. Comparative transcriptomic and proteomic analyses provide insights into the key genes involved in high-altitude adaptation in the Tibetan pig. Sci Rep. 2017,7(1):3654.

23. Zhang B, Shang P, Qiangba Y, Xu A, Wang Z, Zhang H. The association of NR1H3 gene with lipid deposition in the pig. Lipids Health Dis. 2016,15:99.

24. Zhang B, Qiangba Y, Shang P, Lu Y, Yang Y, Wang Z, Zhang H. Gene expression of vascular endothelial growth factor A and hypoxic adaptation in Tibetan pig. J Anim Sci Biotechnol. 2016,7:21.

25. Zhang B, Qiangba Y, Shang P, Wang Z, Ma J, Wang L, Zhang H. A comprehensive microRNA expression profile related to hypoxia adaptation in the Tibetan pig. PLoS One. 2015,10(11):e0143260.

26. 孙新宇,陈雪娇,刘叶,郭阿秀,张浩,张博*.隐性白羽鸡体尺指标、屠宰性能及肉品质的测定与比较分析. 中国畜禽种业, 2026,22(5): 96-100,107.

27. 郭阿秀,张文慧,聂瑞雪,张博*.鸡SMAD2基因组织表达规律及功能解析.中国畜牧杂志,2025,61(04):192-195+205.

28. 程伟,杨爽,旦增洛桑,张博*.HO-1基因对藏猪高原低氧适应性的影响.中国畜牧杂志,2025,61(05):181-186.

29. 普布占堆,张盼,程伟,张博*.西藏隆子县藏香猪产业发展调研报告.中国畜禽种业,2025,21(05):94-101.

30. 刚依晨,普布占堆,李盼,张博*,张浩.MKP-1基因对藏猪高原低氧适应性的影响.中国畜牧杂志,2023,59(10):121-125.

31. 李盼,普布占堆,张浩,张博*.基于全基因组重测序筛选南阳黑猪脂肪沉积相关候选基因.中国农业大学学报,2023,28(08):160-171.

32. 钟海安,张健,旦增洛桑,张博*.基于基因芯片分析西藏山南杂交藏黄牛血统组成.中国畜牧杂志,2023,59(11):166-169+174.

33. 付玉,董新星,严达伟,张浩,张博*. Wnt信号通路在骨骼肌发育中的调控研究进展. 农业生物技术学报, 2022,30(1):164-172.

34. 刘芮佳,张博*,张浩.肌肉注射不同剂量AMH对蛋鸡卵泡选择前后关键基因表达的影响.中国畜牧杂志, 2022, 58(12): 168-173.

35. 苏握瑜,张莹,张浩,张博*.鸡HSPB1基因多态性及其低氧表达差异分析.中国家禽,2022,44(12):1-7.

36. 赵雨农,李盼,段梦琪,商鹏,张博*.藏猪和约克夏猪PGM1基因多态性和表达差异研究. 中国畜牧杂志, 2021, 57 (11): 82-85+94.

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